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Life will not be a state it's a process. The norepinephrine pathway originates from the locus ceruleus (LC) and related brainstem nuclei; the serotonergic neurons originate from the raphe nuclei throughout the brainstem as nicely; the dopaminergic neurons originate in ventral tegmental space (VTA); and the histaminergic pathway originates from neurons in the tuberomammillary nucleus (TMN) of the posterior hypothalamus.

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